Systemic response to infection manifested by two or more of the following:
Temperature > 38 C or < 36 C raised heart rate > 90 /min tachypnoea (respiratory rate > 20 breaths/min or hyperventilation (PaCO2 < 4.25kPa)) White blood cell count > 12 x 10^9/L or < 4 x 10^9 /L or the presence of more than 10% immature neutrophils
Temperature > 38 C or < 36 C
raised heart rate > 90 /min
tachypnoea (respiratory rate > 20 breaths/min or hyperventilation (PaCO2 < 4.25kPa))
White blood cell count > 12 x 10^9/L or < 4 x 10^9 /L or the presence of more than 10% immature neutrophils